Here's what rhymes with antagonistic.
mystic cystic animistic artistic optimistic journalistic mechanistic pessimistic anachronistic autistic ballistic logistic sadistic theistic monistic chauvinistic egotistic sophistic realistic unrealistic deterministic holistic statistic dualistic opportunistic atheistic communistic egoistic hedonistic juristic legalistic novelistic pantheistic patristic polycystic shamanistic surrealistic aphoristic euphemistic casuistic linguistic stylistic heuristic humanistic idealistic monopolistic nationalistic naturalistic simplistic moralistic paternalistic pluralistic rationalistic socialistic synergistic fatalistic impressionistic monotheistic positivistic syllogistic eulogistic polytheistic voyeuristic inartistic jingoistic pugilistic belletristic nepotistic puristic characteristic materialistic probabilistic altruistic capitalistic narcissistic ritualistic futuristic imperialistic militaristic cannibalistic feudalistic overoptimistic relativistic oligopolistic expressionistic individualistic uncharacteristic universalistic spiritualistic sociolinguistic Words that almost rhyme with antagonistic
flyspeck mimic mythic granitic lipstick lytic dipstick diptych nitpick critic analytic civic lyric acidic apocalyptic picnic citric cryptic elliptic physic cynic lithic thymic gimmick triptych sylphic clinic rhythmic terrific catalytic parasitic acrylic ecliptic idyllic limbic pacific paralytic rabbinic satiric arthritic empiric honorific antisemitic patronymic arrhythmic nephritic pantomimic periwig pinprick zoophytic specific scientific intrinsic hemolytic logarithmic monolithic dendritic horrific syphilitic algorithmic haemolytic impolitic neolithic organismic porphyritic philippic cenobitic juridic polyclinic coenobitic bromidic nonrhythmic extrinsic prolific phenotypic proteolytic unscientific antiarrhythmic basophilic hydrolytic metaphysic megalithic saprophytic unspecific bulimic hermaphroditic encephalitic psychoanalytic nonspecific electrolytic hemispheric hydrophilic carboxylic cataclysmic thrombolytic stratospheric nonscientific palaeolithic paleolithic transpacific eosinophilic fibrinolytic hieroglyphic