Here's what rhymes with vicissitudes.

Consider these alternatives

vagaries / bakeries tribulations / relations misfortunes / importance complexities / perplexities quotidian / quotidien humiliations / relations hypocrisies / crises endure / full privations / relations idiosyncrasies / these rigours / course precariousness / gregariousness permeate / late depredations / relations deprivations / relations privation / relation inconveniences / conveniences