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Here's what rhymes with upregulate.

late rate great date weight fate gate plate wait hate relate freight mate regulate trait await bait correlate gait slate grate abate crate fete sate irate pate plait state create straight debate innate isolate update allocate circulate elevate emulate ornate strait aggravate dilate calibrate irrigate oscillate skate spate urinate estate operate illustrate calculate carbonate celebrate cultivate tolerate translate accumulate acetate activate alleviate articulate delegate educate imitate speculate equate liberate ordinate overweight replicate affiliate agitate alienate annihilate emanate emigrate irritate lightweight negate recreate abrogate arbitrate automate escalate incubate inflate innovate insulate obligate pomegranate populate relegate resonate restate sedate segregate upstate indicate separate appreciate eliminate generate accommodate dominate hesitate penetrate stimulate accelerate cooperate dictate formulate integrate mediate originate postulate predicate terminate assimilate collaborate complicate conjugate decorate dedicate deviate elucidate eradicate meditate mitigate motivate navigate propagate situate vertebrate ameliorate congregate consecrate corroborate culminate dissipate distillate extricate fluctuate germinate inculcate legislate liquidate neonate obliterate obviate permeate profligate regenerate reiterate repudiate retaliate stipulate abdicate aspirate attenuate counterweight deprecate excavate expiate explicate extirpate fabricate fascinate gravitate militate officiate overstate perpetrate recapitulate recuperate reinstate saturate venerate vitiate communicate concentrate evaluate facilitate participate compensate incorporate initiate magistrate negotiate contemplate designate discriminate interstate manipulate perpetuate commemorate congratulate delineate deteriorate determinate enumerate evacuate exaggerate predominate assassinate conciliate condensate disseminate evaporate exacerbate proliferate rehabilitate adjudicate confiscate episcopate exonerate extrapolate heavyweight humiliate implicate instigate interrogate intrastate novitiate potentate propitiate reciprocate remonstrate subjugate demonstrate subordinate anticipate precipitate consolidate necessitate underestimate disintegrate expatriate exterminate invalidate authenticate contaminate depreciate emancipate investigate differentiate substantiate intimidate overestimate

Consider these alternatives

upregulation / relation neovascularization / education conduce / use

Words that almost rhyme with upregulate

laid rage rape raid made trade page paid played shape afraid grade wage shade tape blade cage gauge maid prayed weighed bade fade grape sage arrayed babe cape gage arcade braid frayed grenade jade wade stage delayed stayed brigade blockade crusade forbade obeyed parade surveyed unpaid decayed evade repaid scrape spade sprayed swayed upgrade overlaid pervade sh staid strayed decade escape engage betrayed conveyed persuade portrayed invade cascade degrade retrograde barricade lemonade outweighed renegade displayed dismayed dissuade homemade promenade stockade disobeyed masquerade videotape

laced raced raped raked based placed faced shaped taste waste faint paint traced haste saint waist baked chased paste braced chaste draped erased paced taint graced taped replaced quaint spaced acquaint scraped debased effaced staked complaint escaped embraced restraint encased constraint displaced disgraced distaste misplaced vouchsafed
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