Here's what rhymes with methotrexate.

Consider these alternatives

azathioprine / line phenobarbital / phenobarbitol corticosteroids / steroids cyclosporine / seen antidepressant / present paroxetine / seen infliximab / that venlafaxine / seen zidovudine / seen clozapine / line isoniazid / side monotherapy / therapy didanosine / seen vincristine / seen gabapentin / depending amitriptyline / skyline alendronate / late allopurinol / small